Novo’s Next GLP-1 Just Hit 89% A1c Target
Novo Nordisk’s next-generation triple-agonist zenagamtide just hit 89.1% A1c target attainment in phase 2 — one of the highest rates ever reported for a Type 2 diabetes therapy, per the ADA 2026 Scientific Sessions coverage and the Novo Nordisk pipeline announcement. In adults with Type 2 diabetes, the highest dose produced 14.6% body-weight loss and […]
An Oral GLP-1 Just Hit 89% A1c Target
A new phase 2b trial of Eli Lilly’s investigational oral GLP-1 elecoglipron showed that up to 89.6% of participants with Type 2 diabetes reached an A1c of 7% or lower, compared with just 24.9% on placebo —and up to 72.3% achieved at least 5% weight loss versus 20.2% on placebo. The results, presented this week […]
Generic Dapagliflozin Just Got Approved.
The FDA has approved generic versions of dapagliflozin, a workhorse Type 2 diabetes medication in the SGLT2 inhibitor class, and the coverage has been almost entirely about access. Lower cost. More refills. Fewer prior-authorization fights at the pharmacy counter. For the millions of adults in the US who take a daily SGLT2 inhibitor to lower […]
Lilly’s Oral GLP-1 Just Hit Its Numbers. It’s Still Not Reversal.
Eli Lilly’s oral GLP-1, orforglipron, just hit its primary endpoint in the first Phase 3 trial designed to support an FDA submission. The Lilly press release announced results from ACHIEVE-1, published in The New England Journal of Medicine, showing a 1.3%–1.6% A1c reduction and 6.8%–7.9% weight loss in adults with early Type 2 diabetes on […]
The ADA Just Rewrote Its Standards of Care…
The most influential diabetes document in America just dropped. The American Diabetes Association’s Standards of Care in Diabetes — published in December 2025 in Diabetes Care (Volume 49, Supplement 1) and now in effect across U.S. endocrinology practices — is the annual clinical playbook that 90%+ of American endocrinologists follow when treating Type 2 diabetes. […]
This New GLP-1 Pill Hit 89.6% A1c Goal — It Doesn’t Reverse Diabetes
The American Diabetes Association’s 2026 Scientific Sessions wrapped last week in New Orleans, and the headlines read like a victory lap. A new once-daily oral GLP-1 called elecoglipron — a small-molecule pill, no injection, no fasting window — sent 89.6% of patients in its phase 2b trial to an A1c of 7.0% or below. Up […]
UK Doctors Just Made GLP-1s First-Line. 17,000 Lives Saved — and Counting
The UK’s National Institute for Health and Care Excellence (NICE) just rewrote the rulebook for Type 2 diabetes. As of this year, GLP-1 receptor agonists and SGLT-2 inhibitors are being prescribed earlier, faster, and to more patients than ever before — and the agency estimates this shift could prevent around 17,000 deaths over the next […]
Retatrutide Matches Bariatric Surgery: What Diabetics Should Know
New long-term data from the TRIUMPH-1 extension trial — presented at the American Diabetes Association’s 2026 Scientific Sessions — shows retatrutide drove an average of 30.3% body weight loss a 104 weeks, and 65% of participants dropped below the obesity threshold entirely. That puts a weekly injectable in the same conversation as gastric bypass and […]
Lilly’s GLP-1 Pill Just Beat Oral Ozempic – It Still Won’t Reverse Diabetes
The race for the first true GLP-1 pill just ended — and it wasn’t even close. Eli Lilly’s once-daily oral GLP-1,orforglipron, just published head-to-head Phase 3 data showing it beat oral semaglutide (the pill form ofOzempic) on both A1c and weight loss. The results dropped this week in The Lancet, with a separate Phase 3study […]
The New GLP-1 Pill Won’t Reverse Your Type 2 Diabetes
AstraZeneca just reported phase 2 results for a new once-daily GLP-1 pill called elecoglipron. The numbers look great on the surface. The question the press is not asking: does it actually reverse the disease? What the New Study Shows AstraZeneca’s elecoglipron is a once-daily oral GLP-1 receptor agonist — the first of its kind in […]